I Am Haplogroup R1B

I don’t think I ever posted the results of my DNA swab, as described here. Briefly, the National Geographic Society is conducting a rather large study, attempting to map out human history via DNA swabs. Comparatively wealthy citizens of the world pay $100 for their samples, in order to underwrite the collection efforts for less wealthy areas of the world.

Haplogroup R1B M343

Unfortunately, the cool stuff is a Flash file, hidden for participants only, including art samples of Upper Paleolithic man, explanation of the migration to England which my ancestors apparently did, etc. Very cool stuff. Here is what I’ve managed to extract.

How to Interpret Your Results Above are results from the laboratory analysis of your Y-chromosome. Your DNA was analyzed for Short Tandem Repeats (STRs), which are repeating segments of your genome that have a high mutation rate. The location on the Y chromosome of each of these markers is depicted in the image, with the number of repeats for each of your STRs presented to the right of the marker. For example, DYS19 is a repeat of TAGA, so if your DNA repeated that sequence 12 times at that location, it would appear: DYS19 12. Studying the combination of these STR lengths in your Y Chromosome allows researchers to place you in a haplogroup, which reveals the complex migratory journeys of your ancestors. Y-SNP: In the event that the analysis of your STRs was inconclusive, your Y chromosome was also tested for the presence of an informative Single Nucleotide Polymorphism (SNP). These are mutational changes in a single nucleotide base, and allow researchers to definitively place you in a genetic haplogroup.

DNA migration Map
DNA migration Map

Entire migratory history below ‘the fold’. Some of it is beyond my understanding, but it is still fascinating.

 

Haplogroup K M9
Haplogroup K M9

Haplogroup P M45
Haplogroup P M45

Haplogroup R1 M173
Haplogroup R1 M173

Haplogroup R1B M343
Haplogroup R1B M343

 

12 Market Y DNA 2
12 Market Y DNA 2

My immediate ancestry

 

12 Market YDNA
12 Market YDNA

 

 

Your Y chromosome results identify you as a member of haplogroup R1b, a lineage defined by a genetic marker called M343. This haplogroup is the final destination of a genetic journey that began some 60,000 years ago with an ancient Y chromosome marker called M168. The very widely dispersed M168 marker can be traced to a single individual—“Eurasian Adam.” This African man, who lived some 31,000 to 79,000 years ago, is the common ancestor of every non-African person living today. His descendants migrated out of Africa and became the only lineage to survive away from humanity’s home continent.

 

Population growth during the Upper Paleolithic era may have spurred the M168 lineage to seek new hunting grounds for the plains animals crucial to their survival. A period of moist and favorable climate had expanded the ranges of such animals at this time, so these nomadic peoples may have simply followed their food source.

Improved tools and rudimentary art appeared during this same epoch, suggesting significant mental and behavioral changes. These shifts may have been spurred by a genetic mutation that gave “Eurasian Adam’s” descendants a cognitive advantage over other contemporary, but now extinct, human lineages.

Some 90 to 95 percent of all non-Africans are descendants of the second great human migration out of Africa, which is defined by the marker M89.

M89 first appeared 45,000 years ago in Northern Africa or the Middle East. It arose on the original lineage (M168) of “Eurasian Adam,” and defines a large inland migration of hunters who followed expanding grasslands and plentiful game to the Middle East.

Many people of this lineage remained in the Middle East, but others continued their movement and followed the grasslands through Iran to the vast steppes of Central Asia. Herds of buffalo, antelope, woolly mammoths, and other game probably enticed them to explore new grasslands.

With much of Earth’s water frozen in massive ice sheets, the era’s vast steppes stretched from eastern France to Korea. The grassland hunters of the M89 lineage traveled both east and west along this steppe “superhighway” and eventually peopled much of the continent.

A group of M89 descendants moved north from the Middle East to Anatolia and the Balkans, trading familiar grasslands for forests and high country. Though their numbers were likely small, genetic traces of their journey are still found today.

Some 40,000 years ago a man in Iran or southern Central Asia was born with a unique genetic marker known as M9, which marked a new lineage diverging from the M89 group. His descendants spent the next 30,000 years populating much of the planet.

Most residents of the Northern Hemisphere trace their roots to this unique individual, and carry his defining marker. Nearly all North Americans and East Asians have the M9 marker, as do most Europeans and many Indians. The haplogroup defined by M9, K, is known as the Eurasian Clan.

This large lineage dispersed gradually. Seasoned hunters followed the herds ever eastward, along a vast belt of Eurasian steppe, until the massive mountain ranges of south central Asia blocked their path.

The Hindu Kush, Tian Shan, and Himalaya, even more formidable during the era’s ice age, divided eastward migrations. These migrations through the “Pamir Knot” region would subsequently become defined by additional genetic markers.

The marker M45 first appeared about 35,000 to 40,000 years ago in a man who became the common ancestor of most Europeans and nearly all Native Americans. This unique individual was part of the M9 lineage, which was moving to the north of the mountainous Hindu Kush and onto the game-rich steppes of Kazakhstan, Uzbekistan, and southern Siberia.

The M45 lineage survived on these northern steppes even in the frigid Ice Age climate. While big game was plentiful, these resourceful hunters had to adapt their behavior to an increasingly hostile environment. They erected animal skin shelters and sewed weathertight clothing. They also refined the flint heads on their weapons to compensate for the scarcity of obsidian and other materials.

The intelligence that allowed this lineage to adapt and thrive in harsh conditions was critical to human survival in a region where no other hominids are known to have survived.

Members of haplogroup R are descendents of Europe’s first large-scale human settlers. The lineage is defined by Y chromosome marker M173, which shows a westward journey of M45-carrying Central Asian steppe hunters.

The descendents of M173 arrived in Europe around 35,000 years ago and immediately began to make their own dramatic mark on the continent. Famous cave paintings, like those of Lascaux and Chauvet, signal the sudden arrival of humans with artistic skill. There are no artistic precedents or precursors to their appearance.

Soon after this lineage’s arrival in Europe, the era of the Neandertals came to a close. Genetic evidence proves that these hominids were not human ancestors but an evolutionary dead end. Smarter, more resourceful human descendents of M173 likely outcompeted Neandertals for scarce Ice Age resources and thus heralded their demise.

The long journey of this lineage was further shaped by the preponderance of ice at this time. Humans were forced to southern refuges in Spain, Italy, and the Balkans. Years later, as the ice retreated, they moved north out of these isolated refuges and left an enduring, concentrated trail of the M173 marker in their wake.

Today, for example, the marker’s frequency remains very high in northern France and the British Isles—where it was carried by M173 descendents who had weathered the Ice Age in Spain.

Members of haplogroup R1b, defined by M343 are the direct descendents of Europe’s first modern humans—known as the Cro-Magnon people.

Cro-Magnons arrived in Europe some 35,000 years ago, during a time when Neandertals still lived in the region. M343-carrying peoples made woven clothing and constructed huts to withstand the frigid climes of the Upper Paleolithic era. They used relatively advanced tools of stone, bone, and ivory. Jewelry, carvings, and intricate, colorful cave paintings bear witness to the Cro Magnons’ surprisingly advanced culture during the last glacial age.

When the ice retreated genetically homogenous groups recolonized the north, where they are still found in high frequencies. Some 70 percent of men in southern England are R1b. In parts of Spain and Ireland that number exceeds 90 percent.

There are many sublineages within R1b that are yet to be defined. The Genographic Project hopes to bring future clarity to the disparate parts of this distinctive European lineage.

 

 

Eroded Civil Liberties

Truly scary story below. Soon after 9/11, I suspected I was on some list as every time I flew, I was pulled aside and given increased scrutiny. I never missed a flight, but still after 12 straight occurrences (6 flights), I started to worry. However, in my case, (knock on wood-related object), apparently, they cleared me off of the ‘suspect’ list, as I haven’t been searched for the last several flights.

Mr. Moore’s trouble sound a lot worse….
Bush's Brain
James Moore

The Blog | James Moore: Branded | The Huffington Post:

…This week last year I was preparing for a trip to Ohio to conduct interviews and research for a new book I was writing. My airline tickets had been purchased on line and the morning of departure I went to the Internet to print out my boarding pass. I got a message that said, “Not Allowed.” Several subsequent tries failed. Surely, I thought, it’s just a glitch within the airline’s servers or software.
I made it a point to arrive very early at the airport. My reservation was confirmed before I left home. I went to the electronic kiosk and punched in my confirmation number to print out my boarding pass and luggage tags. Another error message appeared, “Please see agent.”

I did. She took my Texas driver’s license and punched in the relevant information to her computer system.

“I’m sorry, sir,” she said. “There seems to be a problem. You’ve been placed on the No Fly Watch List.”

“Excuse me?”

“I’m afraid there isn’t much more that I can tell you,” she explained. “It’s just the list that’s maintained by TSA to check for people who might have terrorist connections.”

“You’re serious?”

“I’m afraid so, sir. Here’s an 800 number in Washington. You need to call them before I can clear you for the flight.”

Exasperated, I dialed the number from my cell, determined to clear up what I was sure was a clerical error. The woman who answered offered me no more information than the ticket agent.

“Mam, I’d like to know how I got on the No Fly Watch List.”

“I’m not really authorized to tell you that, sir,” she explained after taking down my social security and Texas driver’s license numbers.

“What can you tell me?”

“All I can tell you is that there is something in your background that in some way is similar to someone they are looking for.”

“Well, let me get this straight then,” I said. “Our government is looking for a guy who may have a mundane Anglo name, who pays tens of thousands of dollars every year in taxes, has never been arrested or even late on a credit card payment, is more uninteresting than a Tupperware party, and cries after the first two notes of the national anthem? We need to find this guy. He sounds dangerous to me.”

“I’m sorry, sir, I’ve already told you everything I can.”

“Oh, wait,” I said. “One last thing: this guy they are looking for? Did he write books critical of the Bush administration, too?”

I have been on the No Fly Watch List for a year. I will never be told the official reason. No one ever is. You cannot sue to get the information. Nothing I have done has moved me any closer to getting off the list. There were 35,000 Americans in that database last year. According to a European government that screens hundreds of thousands of American travelers every year, the list they have been given to work from has since grown to 80,000.

My friends tell me it is just more government incompetence. A tech buddy said there’s no one in government smart enough to write a search algorithm that will find actual terrorists, so they end up with authors of books criticizing the Bush White House. I have no idea what’s going on.

I suppose I should think of it as a minor sacrifice to help keep my country safe. Not being able to print out boarding passes in advance and having to get to the airport three hours early for every flight is hardly an imposition compared to what Americans are enduring in Iraq. I can force myself to get used to all that extra attention from the guy with the wand whenever I walk through the electronic arches. I’m just doing my patriotic duty.

Of course, there’s always the chance that the No Fly Watch List is one of many enemies lists maintained by the Bush White House. If that’s the case, I am happy to be on that list. I am in good company with people who expect more out of their president and their government.

Hell, maybe I’ll start thinking of it as an honor roll.

found via Tom Tomorrow
home of this great sticker:
Nixon V Bush - available at www.thismodernworld.com

The Wiretappers That Couldn’t Shoot Straight

This outrage always seemed manufactured to me as well, perhaps because I’ve been watching the superlative serial drama, the Wire, recently.

“The Wire – The Complete First and Second Seasons” (Daniel Attias, Alex Zakrzewski, Elodie Keene)

If drug dealers (albeit fictional) from the projects of Baltimore knew in 2002 that cell phone conversations could be monitored, how can President Bunnypants declare with a straight face that ‘security was comprised’ by revealing the extent of warrantless wiretaps?

The Wiretappers That Couldn’t Shoot Straight – New York Times:

ALMOST two weeks before The New York Times published its scoop about our government’s extralegal wiretapping, the cable network Showtime blew the whole top-secret shebang. In its mini-series “Sleeper Cell,” about Islamic fundamentalist terrorists in Los Angeles, the cell’s ringleader berates an underling for chatting about an impending operation during a phone conversation with an uncle in Egypt.

“We can only pray that the N.S.A. is not listening,” the leader yells at the miscreant, who is then stoned for his blabbing.
If fictional terrorists concocted by Hollywood can figure out that the National Security Agency is listening to their every call, guess what? Real-life terrorists know this, too. So when a hyperventilating President Bush rants that the exposure of his warrant-free wiretapping in a newspaper is shameful and puts “our citizens at risk” by revealing our espionage playbook, you have to wonder what he is really trying to hide.

Our enemies, as America has learned the hard way, are not morons. Even if Al Qaeda hasn’t seen “Sleeper Cell” because it refuses to spring for pay cable, it has surely assumed from the get-go that the White House would ignore legal restraints on eavesdropping, just as it has on detainee jurisprudence and torture.
That the White House’s over-the-top outrage about the Times scoop is a smokescreen contrived to cover up something else is only confirmed by Dick Cheney’s disingenuousness. In last week’s oration at a right-wing think tank, he defended warrant-free wiretapping by saying it could have prevented the 9/11 attacks. Really? Not with this administration in charge. On 9/10 the N.S.A. (lawfully) intercepted messages in Arabic saying, “The match is about to begin,” and, “Tomorrow is zero hour.” You know the rest. Like all the chatter our government picked up during the president’s excellent brush-clearing Crawford vacation of 2001, it was relegated to mañana; the N.S.A. didn’t rouse itself to translate those warnings until 9/12.

Given that the reporters on the Times story, James Risen and Eric Lichtblau, wrote that nearly a dozen current and former officials had served as their sources, there may be more leaks to come, and not just to The Times. Sooner or later we’ll find out what the White House is really so defensive about.

Continue reading “The Wiretappers That Couldn’t Shoot Straight”

Who Will Stand Up for the Constitution?

Bob Herbert wonders why Bush the lesser hasn’t been arrested yet

Bob Herbert: Who Will Stand Up for the Constitution?
Why wouldn’t we expect the administration to deceive the public about the illegal spying of the National Security Agency?

Yoosdabee, the Rethuglicans were all for ‘rule of law’….

Continue reading “Who Will Stand Up for the Constitution?”

Harry Reid – Italian Hater, or just racist

I’ve been engrossed in Gus Russo’s book about the Chicago mob, The Outfit

The Outfit (Gus Russo)
“The Outfit” (Gus Russo)

Written in journalistic fashion (copious amounts of research, broadly described events, but no flights of purple prose), the book repeatedly sketches how upperworld corruption was an essential part of The Outfit’s business operation. Bold face names like Tom Pendergast and his protege, Harry Truman, guys like Richard Nixon, Joe (and Jack) Kennedy, various Chicago mayors (Daley the elder, Cermak, etc.), movie moguls like Louis B. Mayer and Harry Cohn, and so on all pop up as equal partners in various criminal schemes.

Surprisingly though, was a minor tidbit about Harry Reid while Gaming Commisioner in Nevada (pgs 347-349 in the paperback edition). Apparently, in the late 1950’s, after Nevada had been turned from a sleepy, two-bit cowboy town into a Rat Pack mecca by ambitious gangsters, the Mormon power-brokers decided that Italians were not to be welcomed anymore. Hence, in 1959 the Gaming Control Act which encouraged licensing to ‘savory characters’ only. However, in the first year of the act, licenses were approved for several convicted WASP bookies, gamblers, tax cheats, bribers, and murderers (such as Charles “Babe” Baron, twice arrested for murder). Italians need not apply – even squeaky clean ones like the gourmet chef, Joseph Pignatello.

Soon the Board instituted

the infamous Black Book, which listed “unsavory characters” who not only could never be licensed, but were barred for life from setting foot in a Las Vegas casino. The introductory remarks noted that the list had been devised so that certain individuals “not discredit the gaming industry”. Discredit gambling? This is the same pastime that the board’s Mormon dogma prohibits and labels immoral. All those listed were so included without formal notification, hearing, or appeal. And the reasons for their inclusion could be mere hearsay. Of the initial eleven placed in the Black Book, eight were Italian, and most had been implicated or convicted in the same sorts of crimes as the WASPs who were licensed:bootlegging and bookmaking.

…Over the years, 62 percent of those placed in the Black Book have been Italian, dwarfing the numbers of the runners-up, Anglo-Saxons (15 percent)…“The mere Italian sound of a man’s name generated considerable suspicion.” In a candid moment, board chairman Harry Reid once said, “The reasons for their being singled out are not important as far as we’re concerned.”

Does this even matter? Somehow, to me, it does. Granted, politicians are as frequently racist, ignorant, jerk-offs as the rest of us, but I dream of leaders who have higher standards then the norm. I had halfway allowed myself to respect Harry Reid, especially after recent comments like:

in May of 2005 when he said of George W. Bush, “The man’s father is a wonderful human being. I think this guy is a loser.”

Oh well, throw him back on the heap. I’m done with him.

Perhaps I’m just sympathetic to profiling, having been searched so many times at airports (12 straight times at one point, though that’s better now, I guess I’ve been taken off the list, knock on wood-like object), attacked by drunken frat boys, or whatever. I still cling to my idealism, regardless of how delusional it is. Blame the hillbilly heroin my doctor recently proscribed for back pain….

Drill Bit Building

Not too sure if this proposed Big Screw building will ever even be built, but certainly is an unusual structure. Seems like it might unbalance the skyline, but the other proposal was for two bulky mid-rise buildings without much style. So, in a binary world, I’d choose the funky over the prosaic. If this were a binary decision, which I don’t think it is.

In Chicago, Plans for a High-Rise Raise Interest and Post-9/11 Security Concerns – New York Times:
In a city known for its skyscrapers, in an era when tall buildings have become targets, can the skyline handle one more that stretches the limit? In Chicago, it seems, the answer may be yes – if the architect is a “starchitect” like Santiago Calatrava.
…Living in the Calatrava tower would not come cheap, by Chicago standards. Mr. Carley said he expected one-bedroom units to sell initially for at least $600,000, with full-floor units of some 7,200-square-feet topping out at $5 million.

The twisting design, which was recently tested in a wind tunnel in Canada, would disperse Chicago’s gusting winds, Mr. Carley said. And Mr. Calatrava designed the interior so that posts and columns would be toward the structure’s center, to allow balconies on some floors and maximize the floor-to-ceiling views.

and the Tribune:

A far less well known developer, Chicago’s Christopher Carley, will unveil his proposal Wednesday for a slender, 115-story tower with a steel spire that could soar higher than 2,000 feet.

Designed by superstar Spanish-born architect and engineer Santiago Calatrava, the skyscraper would rise next to Lake Shore Drive and near the entrance to Navy Pier. Its tapering glass facade would ripple like folds of drapery.

For Carley, the chairman of Fordham Co., the planned hotel and condo tower would be taller than the combined height of his last three previous projects: two towers of roughly 50 stories and an eight-story structure.

Financing for his latest project has not yet been arranged, and will largely depend on achieving prices rarely seen in a downtown market. “Is this going to get done?” Carley said. “It’ll be market-driven.”

But the ambitious proposal, to be called Fordham Spire, would dramatically shift the focus of Chicago’s skyline, and it likely faces community opposition and the challenge of obtaining financing in what some are calling an overheated real estate market.

The Tribune revealed in May that Carley was working with Calatrava–the architect of the bird-like Milwaukee Art Museum addition, the Athens Olympics sports complex and the planned transportation center at Ground Zero–to design a tower on at least one of two sites along the west side of Lake Shore Drive and the north bank of the Chicago River.

Under Carley’s plan, those sites would be combined into a single 2.2-acre parcel at 346 E. North Water St. The area is now an unruly patch, filled with overgrown grass, gravel, trees and a construction trailer.

From it would sprout a tower utterly different from the boxy forms found elsewhere on the Chicago skyline: A skyscraper with gently curving, concave outer walls attached to a massive reinforced concrete core.

Each floor would rotate a little more than 2 degrees from the one below. The floors would turn 270 degrees around the core as they rise, making the building appear to twist.
..
Carley and Calatrava noted that the skyscraper’s thin profile–it would have just 920,000 total square feet, compared with 4.5 million for Sears Tower–would make it a benign, not overbearing, presence along the city’s lakefront.

That is far better, they maintain, than two towers of roughly 50 and 35 stories, which current zoning allows. Towers of that size would be far more bulky and cast greater shadows, the developer and architect argue.

“The tower is without any doubt tall, but it is not big. It is very slender. It is extremely slender,” Calatrava said.

also Eric Zorn weighs in:

Our other major skyscrapers – the Hancock Center, the Sears Tower, the Aon Center and even the upcoming Trump Tower (see the Trib’s Trump Cam for progress) — have a sturdy quality that fits nicely with our town’s nickname, “The City of the Big Shoulders.”
Now what are we supposed to be? “The City of the Big Screw”?

What’s Up with The Shub?

Nora Ephron wonders, again, about that weird incident with the airplane in restricted airspace, which didn’t even merit a call to GWB.

…As you may recall, on May 11, 2005, a small plane made an unauthorized detour into the air space over the nation’s Capitol, setting off a red alert. The Secret Service evacuated Dick Cheney and rushed Laura Bush to a bunker in the White House. The President was not there. He was off riding his bicycle in Beltsville, Maryland, and the Secret Service didn’t notify him about the incident until it was over. At the time they claimed they didn’t want to disturb his bicycle ride.

The internets were blazing with various explanations, maybe the simplest is that Bush isn’t really involved in governing.

Nora goes on:
Nora Ephron: What’s Eating George Bush? | The Huffington Post

But I’ve been wondering about what’s going on with W ever since he emerged from his bizarre groundhog-like vacation and responded to Hurricane Katrina as if he were under water. He had no affect at all. He was almost robotic. His meager vocabulary seemed to have shrunk even further. He conveyed no feeling for the victims — and this was early on, way before anyone realized how many poor people were involved. It was strange. …

At the time I wondered if Bush was on Paxil or Lexapro, drugs that several of my friends are taking and that seem to have turned them into strangely muted versions of themselves. I asked my friend Rita, who’s a shrink, but Rita is very careful about committing on subjects of this sort. She did point out, though, that sometimes, when the President talks, his mouth has a strange sideways twitch, which is apparently common in people who are on antidepressants. …. On the Chris Matthews Show, there was some old footage of the president from last year’s presidential campaign. He was outdoors, talking to a group of people in hard hats; he was energetic, focused, confident, on top of the world. Now you could easily counter: of course he was, it was a lovely day, he was surrounded by supporters, things were going well. But the President we’re seeing these days is a completely different man.

He has, of course, a lot of reasons to be depressed — no point in enumerating them, you know what they are. But most of all, I think he’s depressed because the job has turned out to be so much more onerous than he expected — he said as much to a friend of mine in September. “You have no idea,” he said, “how hard these five years have been.” This is a fairly breathtaking remark given the number of people who, thanks to this president, are now dead as a result of his five years in the Oval Office, but never mind.

The point is that it seems possible to me that when George Bush gave up alcohol in 1986, he dealt with the depression that often accompanies sobriety by becoming an obsessive exerciser. And that’s what he’s essentially done ever since. He’s never held anything that could be confused with a job. Owning a football team [she means baseball team] is not a job. Even being governor of Texas takes only a couple of months a year, it turns out. So he was free to exercise.

But at some point this year, something happened and the exercise regimen stopped working. Bush started becoming depressed. My theory is that a certain amount of panic ensued, and more exercise was prescribed: hence, the afternoon on the bicycle in Maryland, and the reluctance to disturb an already disturbed, irritable man. (Interestingly, the incident happened just after the President returned from a four-day trip to Europe, which had not only required him to work several hours each day but undoubtedly interrupted his exercise routine.) Then came the vacation in August, the odd, sequestered vacation, a perfect time for the President’s doctor to try medication, or change medication, or adjust medication. Then Katrina and the emergence in the fall of an unenergetic, irritable, muted, unfocussed President, the man you see today.

Look it up: depression + symptoms. You’ll read it for yourself: loss of energy, irritability, feeling “slowed down,” inability to concentrate.

Plenty of people have noticed that something is altered in George Bush’s affect. We’ve speculated, on these pages, and elsewhere, that Bush is suffering the after-effects of a stroke, or of a reoccurrence of alcoholism, or that he’s started snorting coke again, or perhaps he is on some sort of anti-depressent. Something certainly seems different from 1999.

Track Your Kit

Door

The next step of our DNA samples has been completed:

Track Your Kit – The Genographic Project:
DNA ANALYSIS AND QUALITY CONTROL
The samples are transferred into PCR amplification plates for testing using a robotic liquid handling station. The appropriate chemicals are added to the samples to amplify the targeted regions of the DNA for testing. The samples are heated and cooled in a thermal cycler in order to run the PCR amplification. The PCR amplification products are loaded into the capillary electrophoresis machine and the products are sorted by size and color.
A laboratory staff member uses a computer program to assign scores to the samples. The computer generated scores are then reviewed by two additional laboratory staff members to produce finalized data.

The Great Genographic Project

Venetian Night

Our DNA samples have moved to the next step in the Genographic Project….

Track Your Kit – The Genographic Project:
DNA ISOLATION
The cells are broken open by incubation with a protein-cutting enzyme overnight. Chemicals and the samples are transferred into deep well blocks for robotic DNA isolation. The blocks of chemicals and samples are placed on the extraction robot. The robotic DNA isolation uses silica-coated iron beads. In the presence of the appropriate chemicals DNA will bind to silica. The robot then uses magnetic probes to collect the beads (and DNA) and transfer them through several chemical washes and finally into a storage buffer, which allows the beads to release the DNA. At this point the beads are collected and discarded.

Track Your Kit – The Genographic Project

Tall statue aka Our Onion-headed Overlords

Our DNA has made it to Houston, and is currently being isolated.

Track Your Kit – The Genographic Project:
ARRIVAL AND BATCH CREATION
The kits are received at the Houston office of Family Tree DNA and checked in. All of the kits are assigned to a batch and shipped to the Arizona Research Labs at the University of Arizona. The samples are received at the university and the orders are transferred to a computer system. The computer sorts the orders and assigns each sample to a specific location in one of many sample grids As the barcodes on the samples are read the computer directs the researchers where to place each sample (which tray and which coordinates).

National Geographic Genographic Project

We received our swab sample kits for the Genographic Project in the mail. Have to avoid liquids, especially warm liquids, for an hour before collecting the first inner-cheek sample. Eight hours later, same procedure. We will probably collect our DNA in the morning.

The fine print reiterates that everything is anonymously tabulated, then the actual cells are discarded. So, unless some freak accident happens, no clones of us will be created ten years from now. Sounds like a Hollywood B movie plot though, I should do a treatment.

Park Life particle Man

I thought these amusing, from the extensive FAQ:

Are any pharmaceutical or insurance companies involved in the Genographic Project? No. The Genographic Project is supported by private foundations in conjunction with National Geographic and IBM, the project’s lead partner.

 

Is the Genographic Project bio-prospecting? No. the Genographic Project research centers will release the resulting genetic data (on an anonymous and aggregate basis) into the public domain to promote further research. The genetic data will be treated as discoveries, rather than inventions, and will not be patented.

Is the Genographic Project linked to any medical research? No. The samples collected from the indigenous groups as well as the samples submitted by the general public via the Public Participation Kits will be analyzed for historical and anthropological data.

From the Beeb:

“There are still many questions we haven’t answered. Was there any interbreeding with Neanderthals as modern humans moved into Europe? Did any of the migrations to the Americas come across the Pacific – or even the Atlantic?”

These and other unanswered questions form the research goals of the project. They include:

• Who are the oldest populations in Africa – and therefore the world?

•Did Alexander the Great’s armies leave a genetic trail?

• Who were the first people to colonise India?

• Is it possible to obtain intact DNA from the remains of Homo erectus and other extinct hominids?

• How has colonialism affected genetic patterns in Africa?

• Was there any admixture with Homo erectus as modern humans spread throughout South-East Asia?

• Is there any relationship between Australian Aboriginal genetic patterns and their oral histories?

• What are the origins of differences between human groups?

A total of 10 DNA collection centres located around the world will focus on obtaining samples from indigenous peoples. The genetic markers in the blood of these groups have remained relatively unchanged for generations.

 

update: results here

Your Genetic Journey – The Genographic Project

The National Geographic has initiated a very unusual genetic project. You send them a cheek swab (via a $107 kit), and they do a detailed workup on your genetic ancestry. I think I’m doing it as a belated birthday present to myself. Just hope it isn’t some Patriot Act related subterfuge….

 

Your Genetic Journey – The Genographic Project:
Once you have purchased your own Genographic Project Public Participation Kit, you can begin the exploration into your deep ancestry. The first step involves a painless cheek swap to acquire a DNA sample. Once you have completed the cheek swabbing process, you will secure the swabs inside the transport tubes and mail the tubes off to the lab using the supplied envelope. It’s that simple, and guaranteed anonymous.
Your haplogroup’s story may evolve as the Genographic Project collects thousands of DNA samples during the next few years. When it does, tantalizing new chapters will be added to this website and your information will be updated.

 

The entire online process is completely anonymous so no one, including project scientists, will ever be able to access your results. But, if you choose, you can share them. A printable, hi-resolution certificate of participation, map, and haplogroup overview serve as compelling documentation of your deep ancestry.

 

link via boing boing

Michael Jordan shaved head look

I’m watching a classic 1988 Bulls vs. Pistons game (first aired on April 3, 1988) on NBA-TV, and I figured out why Jordan shaved his head the following summer. In this game, Jordan still has his normal hair, but is rapidly thinning in front. Somewhere buried on the Bulls bench (and playing a few minutes in 1st Q/2nd Q) is a center Granville Waiters, who had an advanced state of male pattern baldness, as much as Bozo the Clown in fact.

I’m sure a young Jordan, razzing Waiters one day in practice suddenly realized that he might be next, and decided to shave his remaining hair off to avoid the embarrassment. Perfectly logical.

update, rewound the TiVo, and Waiters definitely was the guy that started the trend. See this photo. Nuff said…

Granville Waiters

Granville Waiters as a Rocket

Jordan’s Hair Trigger, as it were. Ahem

Stringer Bell


“The Wire: The Complete Series” (Clark Johnson, Agnieszka Holland, Alex Zakrzewski, Anthony Hemingway, Brad Anderson)

The next to last episode of my favorite television hour, The Wire, rubbed out Stringer Bell…. Whacked! Another HBO Main Player Meets His End:

Fans of HBO’s hit crime series “The Wire” may have been shocked off their couches last night when one of the show’s main characters, the calculating drug dealer Stringer Bell, was gunned down in a gruesome ambush.

But it is unlikely that anyone in the Sunday-night audience was as stunned as Idris Elba, the 32-year-old actor who has brought Stringer to life since “The Wire” began three years ago. “When I first read the script I was like: ‘What? No! This isn’t supposed to happen,’ ” Mr. Elba said over dinner at an Upper West Side restaurant. “I was deeply disappointed. It was a surprise, a complete surprise.”

Mr. Elba, who is far more sensitive than the stoic Stringer, said his last day of work was particularly emotional. Michael K. Williams, who plays Omar Devone Little, the gay, shotgun-toting thug who blasts away Stringer, said: “There were a lot of wet eyes on the set. I just had to keep telling myself that Idris is alive and he has a bright future ahead of him.”

Fans of the show may be surprised to learn that Mr. Elba is not African American. The only child of a mother from Ghana and father from Sierre Leone, Mr. Elba was born and brought up in Hackney, a working-class borough of London. It is a fact he reluctantly shares with fans, preferring instead to use his American accent when talking with those who request autographs. “Wherever I go the real hard-core dudes come up to me and confide in me,” said Mr. Elba, who over the years has been approached by dozens of drug dealers identifying with Stringer. “I almost feel guilty turning around and saying: ‘Hello, mate. My name’s Idris and I’m from London.’ ” Mr. Elba burst into an exaggerated version of his cockney accent. “I don’t want to break the illusion.”

I’d pay to see that particular interaction….

Knock Knock

Yes, I’m a little bit obsessed with playlists. This post triggered a quick browse through my iTunes library. I didn’t bother with all the variants of Knockin’ On Heavens Door by Bob Dylan, there are literally dozens, and not all are worth hearing very often. The original is my favorite: from the Sam Peckinpah western, Pat Garrett & Billy the Kid. Also ignored a few other covers of that song by other artists, but this list as configured isn’t bad. My favorite is probably still the Rolling Stones song, too bad Mick Taylor didn’t last longer with the band: those records are the best albums they ever recorded.

  1. B.B. KingBowlegged Woman, Knock-Kneed Man
    More Treasures From The Vault
  2. Jay-ZCan’t Knock The Hustle
    Jay-Z Unplugged
  3. Rolling StonesCan’t You Hear Me Knocking
    Sticky Fingers
  4. Fats DominoDon’t Come Knockin’
    Fats Domino – Walking to New Orleans (Disc 3)
  5. Mavis StaplesDon’t Knock
    You Are Not Alone
  6. Pickett, WilsonDon’t Knock My Love (Part 1)
    Greatest Hits
  7. Jay-ZHard Knock Life
    Chapter One
  8. Dave EdmundsI Hear You Knocking
    Rockpile
  9. Fats DominoI Hear You Knocking
    Fats Domino – Walking to New Orleans (Disc 3)
  10. Smiley LewisI Hear You Knocking
    Doctors, Professors, Kings & Queens
  11. Little RichardKeep A Knockin’
    Uncut Not Fade Away: 15 Classics That Fired Up The Rolling Stones
  12. Sonics, TheKeep A Knockin’
    Here Are The Sonics!!!
  13. Louis Jordan & His Tympany FiveKeep A Knockin’ But You Can’t Come In
    Disc A: 1938-1940
  14. Fleetwood MacKeep A Knocking
    The Early Years
  15. Little RichardKeep On Knockin’
    Greatest Gold Hits
  16. DeathKeep On Knocking
    Uncut: May 2010 Search And Destroy
  17. Mississippi John HurtKeep On Knocking
    The Immortal Mississippi John Hurt
  18. Allen, LilyKnock ’em Out
    Uncut August 2006
  19. WeezerKnock Down Drag Out
    Weezer (Green Album)
  20. HivesKnock Knock
    Veni Vidi Vicious
  21. Louis Jordan & His Tympany FiveKnock Me A Kiss
    Disc B: 1941-1944
  22. La’s, TheKnock Me Down
    The La’s
  23. Redding, OtisKnock On Wood (w/ Carla Thomas)
    The Very Best Of Otis Redding, Vol 2
  24. The UpsettersKnock Three Times
    Trojan Upsetter Box Set (Disc 1)
  25. The Humane SocietyKnock, Knock
    Nuggets: Original Artyfacts From The First Psychedelic Era, Vol. 3
  26. Kings Of LeonKnocked Up
    Because Of The Times
  27. Armstrong, LouisKnockin’ A Jug
    Hot Fives & Sevens Volume 3
  28. Lil GreenKnockin’ Myself Out
    Reefer Songs
  29. Antony & The JohnsonsKnockin’ On Heaven’s Door
    I’m Not There
  30. Booker T. JonesKnockin’ On Heaven’s Door
    How Many Roads: Black America Sings Bob Dylan
  31. Denny, SandyKnockin’ On Heaven’s Door
    Who Knows Where The Time Goes – Disc 3
  32. Dylan, BobKnockin’ On Heaven’s Door
    Pat Garrett & Billy The Kid
  33. Ferry, BryanKnockin’ On Heaven’s Door
    Dylanesque
  34. Grateful DeadKnockin’ on Heaven’s Door
    Knockin’ on Heaven’s Door
  35. Guns N’ RosesKnockin’ On Heaven’s Door
    Use Your Illusion II
  36. LucianoKnockin’ On Heaven’s Door
    Is It Rolling Bob?
  37. U2Knockin’ On Heaven’s Door
    Covering ‘Em
  38. Warren ZevonKnockin’ On Heaven’s Door
    The Wind
  39. The UnknownKnockin’ On Heaven’s Door Dub
    Is It Rolling Bob?
  40. Dylan, BobKnockin’ On Heavens Door
    Live 1975 – The Rolling Thunder Revue (Bootleg Series Vol. 5)
  41. Nick Cave & The Bad SeedsKnockin’ On Joe
    The Firstborn Is Dead
  42. Elmore JamesKnocking At Your Door
    Uncut – April 2008 – When The Levee Breaks
  43. Uncle TupeloKnocking On heavens door
    Colorblind & Rhymeless
  44. Wonder, StevieKnocks Me Off My Feet
    Songs In The Key of Life
  45. Bonnie “Prince” BillyKnockturne
    I See A Darkness
  46. Sharon Jones & The Dap-KingsLet Them Knock
    100 Days, 100 Nights
  47. LL Cool JMama Said Knock You Out (w/ Bob Dylan intro)
    Bob Dylan – Theme Time 2 Mother
  48. Gil Scott-HeronNo Knock
    The Revolution Will Not Be Televised
  49. Social DistortionShe’s A Knockout
    Social Distortion
  50. Plant, Robert and the Strange SensationSomebody Knocking
    Mighty Rearranger
  51. Louis Jordan & His Tympany FiveThat’ll Just ‘Bout Knock Me Out
    Disc B: 1941-1944